P1545: DURABILITY OF HEMOGLOBIN RESPONSE AND REDUCTION IN TRANSFUSION BURDEN IS MAINTAINED OVER TIME IN PATIENTS WITH PYRUVATE KINASE DEFICIENCY TREATED WITH MITAPIVAT IN A LONG-TERM EXTENSION STUDY

• R. F. Grace,
• A. Glenthøj,
• W. Barcellini,
• M. Verhovsek,
• J. A. Rothman,
• M. Morado Arias,
• D. M. Layton,
• O. Andres,
• F. Galactéros,
• E. J. van Beers,
• K. Onodera,
• V. Viprakasit,
• S. Chonat,
• J. B. Porter,
• M. P. Judge,
• P. A. Kosinski,
• P. Hawkins,
• S. Gheuens,
• R. Xu,
• B. McGee,
• V. Beynon,
• H. Al-Samkari

Affiliations

R. F. Grace

1 Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Boston, MA, United States of America

A. Glenthøj

2 Department of Haematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark

W. Barcellini

3 Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

M. Verhovsek

4 McMaster University, Hamilton, ON, Canada

J. A. Rothman

5 Duke University Medical Center, Durham, NC, United States of America

M. Morado Arias

6 Hematology Department, Hospital Universitario La Paz, Madrid, Spain

D. M. Layton

7 Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom

O. Andres

8 Department of Paediatrics, University of Würzburg, Würzburg, Germany

F. Galactéros

9 Unité des Maladies Génétiques du Globule Rouge, CHU Henri Mondor, Creteil, France

E. J. van Beers

10 Van Creveldkliniek, Department of Internal Medicine, University Medical Center Utrecht, Utrecht, Netherlands

K. Onodera

11 Tohoku University Hospital, Sendai, Japan

V. Viprakasit

12 Siriraj Hospital, Mahidol University, Bangkok, Thailand

S. Chonat

13 Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, GA, United States of America

J. B. Porter

14 Haematology Department, University College London Hospitals, London, United Kingdom

M. P. Judge

15 Agios Pharmaceuticals, Inc., Cambridge, MA

P. A. Kosinski

15 Agios Pharmaceuticals, Inc., Cambridge, MA

P. Hawkins

15 Agios Pharmaceuticals, Inc., Cambridge, MA

S. Gheuens

15 Agios Pharmaceuticals, Inc., Cambridge, MA

R. Xu

15 Agios Pharmaceuticals, Inc., Cambridge, MA

B. McGee

15 Agios Pharmaceuticals, Inc., Cambridge, MA

V. Beynon

15 Agios Pharmaceuticals, Inc., Cambridge, MA

H. Al-Samkari

16 Division of Hematology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America