Primary diffuse large B-cell lymphoma of the frontal sinus: A case report and literature review

Hiroshi Nagafuji, MD; Hidenori Yokoi, MD; Arisa Ohara, MD; Masachika Fujiwara, MD; Nobuyuki Takayama, MD; Koichiro Saito, MD

Radiology Case Reports (Jun 2018)

Primary diffuse large B-cell lymphoma of the frontal sinus: A case report and literature review

Hiroshi Nagafuji, MD,
Hidenori Yokoi, MD,
Arisa Ohara, MD,
Masachika Fujiwara, MD,
Nobuyuki Takayama, MD,
Koichiro Saito, MD

Affiliations

Hiroshi Nagafuji, MD: Department of Otolaryngology, Head and Neck Surgery, Kyorin University School of Medicine, Tokyo 181-8611, Japan
Hidenori Yokoi, MD: Department of Otolaryngology, Head and Neck Surgery, Kyorin University School of Medicine, Tokyo 181-8611, Japan; Corresponding author.
Arisa Ohara, MD: Department of Radiology, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo 181-8611, Japan
Masachika Fujiwara, MD: Department of Pathology, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo 181-8611, Japan
Nobuyuki Takayama, MD: Second Department of Internal Medicine, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo 181-8611, Japan
Koichiro Saito, MD: Department of Otolaryngology, Head and Neck Surgery, Kyorin University School of Medicine, Tokyo 181-8611, Japan

Journal volume & issue: Vol. 13, no. 3
pp. 635 – 639

Abstract

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Diffuse large B-cell lymphoma arising as a primary tumor in the frontal sinus is very rare. Moreover, it is often difficult to diagnose frontal sinus lesions. A 67-year-old Japanese man initially presented with diplopia and a swollen left upper eyelid. Diffusion-weighted magnetic resonance imaging suggested a malignant lymphoma of the frontal sinus, and subsequent extensive examination revealed diffuse large B-cell lymphoma of the frontal sinus with left orbital invasion. Six courses of combined immunodirected chemotherapy were administered. The patient is tumor-free owing to the accurate diagnosis of lymphoma at an early stage. Keywords: Sinonasal non-Hodgkin lymphoma, Frontal sinus, Diffusion-weighted magnetic resonance imaging, Apparent diffusion coefficient

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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