NONALCOHOLIC FATTY LIVER DISEASE AND CARDIOVASCULAR COMPLICATIONS -WHAT IS THE RELATIONSHIP?

Abstract

Nonalcoholic fatty liver disease (NAFLD) is one of the most common diseases in hepatology, which leads to a deterioration in the quality of life, disability and death. NAFLD occurs in all age groups, but the most vulnerable are women aged 40-60 years with signs of metabolic syndrome (MS). After being diagnosed NAFLD patients should be screened for the presence of their associated diseases, such as metabolic syndrome and cardiovascular disease. During the past years the role and function of adipose tissue was restudied, what leaded to the active scientific study of the molecular mechanisms of biosynthesis of fat producing hormones and their role in the development of obesity, insulin resistance and associated cardiovascular disease. All medical researches carried out in this area are promising and relevant, but the data are rather contradictory and require further research to produce new true facts that could form the basis for new diagnostic and therapeutic strategies for metabolic abnormalities in patients with cardiovascular disease.

Keywords

• жировая болезнь печени
• сердечно-сосудистая патология
• метаболический синдром
• fatty liver disease
• cardiovascular disease
• metabolic syndrome