Targeting tumor microenvironment with antibody-guided IL-2 pro-cytokine promotes and rejuvenates dysfunctional CD8+ T cells

• Xue Wang,
• Longchao Liu,
• Tao Yue,
• Zhichen Sun,
• Joonbeom Bae,
• Kuo-Fu Tseng,
• Anli Zhang,
• Jian Qiao,
• Yang-Xin Fu

Affiliations

Xue Wang

Department of Pathology, University of Texas Southwestern Medical Center

Longchao Liu

CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences

Tao Yue

Aetio Biotherapy

Zhichen Sun

Department of Pathology, University of Texas Southwestern Medical Center

Joonbeom Bae

Department of Pathology, University of Texas Southwestern Medical Center

Kuo-Fu Tseng

Aetio Biotherapy

Anli Zhang

Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center

Jian Qiao

Department of Pathology, University of Texas Southwestern Medical Center

Yang-Xin Fu

Department of Pathology, University of Texas Southwestern Medical Center