Circ_0000144 acts as a miR-1178-3p decoy to promote cell malignancy and angiogenesis by increasing YWHAH expression in papillary thyroid cancer

Abstract

Highlights 1. Inhibition of circ_0000144 repressed malignant behaviors and angiogenesis of PTC cells in vitro. 2. Knockdown of circ_0000144 constrained PTC cell proliferation in vivo. 3. Circ_0000144 acted as a miR-1178-3p sponge. 4. YWHAH acted as a downstream target for miR-1178-3p.

Keywords

• PTC
• Circ_0,000,144
• miR-1178-3p
• YWHAH
• Angiogenesis