Vaccination Status and Effectiveness of COVID‐19 Vaccines in Patients with Prostate and Bladder Cancer

Abstract

Considering the importance of understanding COVID-19 prevalence and vaccine effectiveness in individuals dealing with bladder or prostate cancer, as well as the plausible adverse repercussions of immunization, this study was undertaken to assess the prevalence and vaccination rates of COVID-19 in this group of patient. Furthermore, the investigation seeks to evaluate potential adverse effects and the efficacy of vaccines in patients diagnosed with prostate and bladder cancer. In this cross-sectional study conducted from 2020 to 2022, we systematically extracted clinical and demographic information, COVID-19 diagnoses, clinical symptoms, and paraclinical data from the bladder and prostate cancer registry at our institution. Our analysis encompassed assessing the frequency of COVID-19 infections, vaccination rates, and the occurrence of adverse effects associated with vaccination within this specific cohort. Among the 249 enrolled patients, COVID-19 infection was confirmed in 19.4% of bladder cancer patients and 16.6% of prostate cancer patients. A substantial majority, 81% (202 patients), had received vaccination, with the Sinopharm vaccine being the preferred choice for the majority (90%). The study's outcomes reveal a vaccine efficacy of 82% in individuals with bladder cancer, while displaying a higher efficacy of 96% among patients with prostate cancer. This study provides evidence supporting the efficacy of the SARS-CoV-2 vaccine in reducing COVID-19-associated complications and mortality, as well as its high efficacy in patients with prostate and bladder cancer.

Keywords

• COVID-19
• vaccination
• prostate cancer
• bladder cancer