Synthesis and Characterization of Novel Oxazolidinones Via Schiff Base Reactions

Abstract

A number of new novel 2,3-disubstituted-1,3-oxazolidine-5-one derivatives were synthesized by the reaction of Schiff‘s bases with chloroacetic acid in dry banzene with high yields. Schiff bases were synthesized by the reaction of heteroaromatic aldehydes or ketones with primary heterocyclic amines. The products were identified by their melting points and spectral features ( FT-IR and UV-Vis-spectra and 1HNMR spectra ).

Keywords

• oxazolidinones
• schiff base
• chloroacetic acid