Gaceta Mexicana de Oncología (Jul 2022)

Evaluation of sialic acid concentrations and its association with the use of hormonal contraceptives

  • Andrea G. Rodríguez-López,
  • Mónica L. Córdova-Serrano,
  • Ana L. González-Bolaños,
  • Karen B. Téllez-Blanco,
  • Laura S. Marín-Jaureguí,
  • Ma. José Santoyo-Treviño,
  • Aida C. Hernández-Arteaga

DOI
https://doi.org/10.24875/j.gamo.22000081
Journal volume & issue
Vol. 21, no. 3

Abstract

Read online

Objective: To evaluate the relationship between the use of HC and the concentration of Sialic acid (CSA) detected in the saliva of 120 women from San Luís Potosí, Mexico. Methods: Three groups were evaluated: control group, HC intake shorter than 4 years, and HC intake longer than 4 years. A questionnaire was applied, anthropometric measures were taken, and collection of saliva samples was carried out. The samples were analyzed with Raman-SERS, for which silver nanoparticles were synthesized, and the measurement of SA was held. Results: The concentrations were divided into three SA groups: normal (≤ 4 mg/dL), risk (> 4-7 mg/dL), and altered (> 7 mg/dL). The maximum CSA was detected, which was 9.2 mg/dL. All the volunteers who used the intrauterine system (IUS) and most of the ones who used the pills and subdermal implant (SI) presented risk and altered concentrations. Conclusions: That there is an association between the HC and the CSA, presenting a higher concentration, those volunteers who used IUS, contraceptive pills, and SI.

Keywords