Natural surfactants assisted an efficient synthesis of tetrahydro-β-carbolines

Abstract

An expeditious protocol for the synthesis of structurally diversified β-carboline derivatives has been reported using a readily available natural surfactant medium. The synthesis of β-carboline derivatives in good yields under optimized conditions was carried out by the reaction of tryptamine with aldehydes in an aqueous extract of Acacia Concinna pods. The use of an aqueous medium, ease of purification, good yield and cost-effective reaction suggest for bulk scale production β-carboline derivatives.

Keywords

• Acacia concinna
• β-carboline
• Tryptamine
• Aldehyde
• Green and clean reaction