Technology in Cancer Research & Treatment (Aug 2024)

Exosomes in Renal Cell Cancer: Diagnostic and Therapeutic Nanovehicles

  • Stergios Boussios MD, MSc, PhD, FRCP,
  • Saak V. Ovsepian MSc, PhD

DOI
https://doi.org/10.1177/15330338241275403
Journal volume & issue
Vol. 23

Abstract

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Early diagnosis is crucial for enhancing the survival rate of renal cell cancer patients, and exosomes present potential advantages in this area. Their small size, high mobility, and lipid bilayer structure enable exosomes to cross biological membranes easily, protecting the bioactive cargo within from degradation. Exosomes significantly influence the invasion and metastasis of RCC, and they also contribute to tumor drug resistance and immune evasion.