Global trends in oxidative stress in the Retina: A bibliometric analysis of 2013–2023
Meng Xiong,
Chang Yu,
Baoping Ren,
Meiqi Zhong,
Jing Lu,
Chengzhi Yuan,
Qifang Sun,
Qinghua Peng,
Meiyan Zeng,
Houpan Song
Affiliations
Meng Xiong
Hunan Provincial Key Laboratory of Traditional Chinese Medicine Diagnostics, Hunan University of Chinese Medicine, Changsha, Hunan, China; School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China
Chang Yu
Hunan Provincial Key Laboratory of Traditional Chinese Medicine Diagnostics, Hunan University of Chinese Medicine, Changsha, Hunan, China; School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China
Baoping Ren
Hunan Provincial Key Laboratory of Traditional Chinese Medicine Diagnostics, Hunan University of Chinese Medicine, Changsha, Hunan, China; School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China
Meiqi Zhong
Hunan Provincial Key Laboratory of Traditional Chinese Medicine Diagnostics, Hunan University of Chinese Medicine, Changsha, Hunan, China; School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China
Jing Lu
Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China; School of Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China
Chengzhi Yuan
Hunan Provincial Key Laboratory of Traditional Chinese Medicine Diagnostics, Hunan University of Chinese Medicine, Changsha, Hunan, China; School of Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China
Qifang Sun
Hunan Provincial Key Laboratory of Traditional Chinese Medicine Diagnostics, Hunan University of Chinese Medicine, Changsha, Hunan, China; School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China
Qinghua Peng
Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China
Meiyan Zeng
School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China; Corresponding author. School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, 300 Xueshi Road, Yuelu District, Changsha, Hunan, 410208, China.
Houpan Song
Hunan Provincial Key Laboratory of Traditional Chinese Medicine Diagnostics, Hunan University of Chinese Medicine, Changsha, Hunan, China; School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China; Hunan Provincial Key Laboratory for Prevention and Treatment of Ophthalmology and Otolaryngology Diseases with Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China; Corresponding author. Hunan Provincial Key Laboratory of Traditional Chinese Medicine Diagnostics, Hunan University of Chinese Medicine, 300 Xueshi Road, Yuelu District, Changsha, Hunan 410208, China.
Background: Oxidative stress plays a significant role in the pathogenesis of many retinal diseases. However, only a few systematic bibliometric studies have been conducted. This study aims to visualize research hotspots and developmental trends in oxidative stress in the retina from 2013 to 2023 by analyzing bibliometric data. Methods: We retrieved papers on oxidative stress in the retina published between 2013 and 2023 from the Web of Science Core Collection. The data were visually analyzed using CiteSpace and VOSviewer software. Results: The total number of 2100 publications were included in the analysis. An overall increasing trend in the number of publications is observed between 2013 and 2023. Chinese publications were the most contributive, but United States publications were the most influential. Shanghai Jiao Tong University was the most active and prolific institution. Antioxidants was the most productive journal, while Oxidative Medicine and Cellular Longevity were the journals with the most-cited articles. Kaarniranta K, from Finland, was the most productive and influential author. Examination of co-cited references revealed that researchers in the field are primarily focused on investigating the molecular mechanisms, preventive strategies, and utilization of antioxidants to address retinal oxidative damage. Diabetic retinopathy, endothelial growth factor, retinitis pigmentosa, retinal degeneration, antioxidant response, retinal ganglion cells, and genes are the research hotspots in this field. Metabolism, sodium iodate, and system are at the forefront of research in this field. Conclusion: Attention toward retinal oxidative stress has increased over the past decade. Current research focuses on the mechanisms of retinal diseases related to oxidative stress and the experimental study of antioxidants in retinal diseases, which may continue to be a trend in the future.
