Frontiers in Genetics (Apr 2023)

A review on the role of LINC00511 in cancer

  • Soudeh Ghafouri-Fard,
  • Arash Safarzadeh,
  • Bashdar Mahmud Hussen,
  • Mohammad Taheri,
  • Mohammad Taheri,
  • Seyed Abdulmajid Ayatollahi

DOI
https://doi.org/10.3389/fgene.2023.1116445
Journal volume & issue
Vol. 14

Abstract

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Long Intergenic Non-Protein Coding RNA 511 (LINC00511) is an RNA gene being mostly associated with lung cancer. Further assessments have shown dysregulation of this lncRNA in a variety of cancers. LINC00511 has interactions with hsa-miR-29b-3p, hsa-miR-765, hsa-mir-150, miR-1231, TFAP2A-AS2, hsa-miR-185-3p, hsa-miR-29b-1-5p, hsa-miR-29c-3p, RAD51-AS1 and EZH2. A number of transcription factors have been identified that regulate expression of LINC00511. The current narrative review summarizes the role of LINC00511 in different cancers with an especial focus on its prognostic impact in human cancers.

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