Nature Communications (Sep 2019)

Multifunctional nanoagents for ultrasensitive imaging and photoactive killing of Gram-negative and Gram-positive bacteria

  • Jiali Tang,
  • Binbin Chu,
  • Jinhua Wang,
  • Bin Song,
  • Yuanyuan Su,
  • Houyu Wang,
  • Yao He

DOI
https://doi.org/10.1038/s41467-019-12088-7
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 14

Abstract

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The authors present multifunctional nanoagents that can be used for imaging and treatment of bacterial infections. The nanoagents are made of fluorescent silicon nanoparticles functionalized with a glucose polymer and loaded with chlorin e6, and are taken up by bacteria via ABC transporters.