Heliyon (Sep 2024)

A patient with primary intracranial granuloma with difficulty in differential diagnosis: A case report and literature review

  • Wentao Liang,
  • Zhou Qi,
  • Hu Yang,
  • Liang Niu,
  • Qiao Li,
  • Shiwen Guo,
  • Yawen Pan

Journal volume & issue
Vol. 10, no. 18
p. e37709

Abstract

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There are few reports about primary intracranial granulomas without an identifiable infectious history. A 25-year-old male with intracranial granuloma. The patient presented with a history of tinnitus with intermittent headache for 1 week. Consequently, MRI showed pronounced and extensive enhancement lesions in the left frontal lobe involved in the cerebral longitudinal fissure cistern and the inside of the right frontal lobe, accompanied by a moderate degree of oedema; The lesion was a pilomyxoid astrocytoma preoperatively. Following a systemic examination, gross total resection of the lesion was performed, and postoperative pathological examination revealed the presence of inflammatory lesions. The patient exhibited notable symptom amelioration post-surgery, leading to discharge after the treatment. Subsequently, a sequential treatment involving steroid therapy was administered, resulting in successful patient recovery.

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