International Medical Case Reports Journal (Dec 2020)
A Fibroblast-Derived Human Growth Factor Preparation for the Management of Acute Radiodermatitis: A Case Report
Abstract
Georgia Vadarli,1 Maria Angelo-Khattar2 1Plastic Surgery Consultancy Private Practice, Thessaloniki, Greece; 2American Academy of Anti-Aging Medicine (A4M), Dubai, United Arab EmiratesCorrespondence: Maria Angelo-Khattar POB 5956, Dubai, United Arab EmiratesTel +971506245494Email [email protected]: Radiotherapy is a commonly used modality in breast cancer management. Amongst the consequences of treatment are acute and/or chronic skin changes, which often lead to itching, pain, and a diminished aesthetic appearance, all of which greatly impact the patient’s quality of life. Management of radiation-induced skin effects has not as yet been standardized, with various protocols being applied by different radiotherapy departments. This case study outlines the management of a grade 3 acute radiodermatitis in a female with a synergistic preparation of anti-inflammatory cytokines and growth factors derived from human fibroblasts. The treatment resulted in the total resolution of the radiation-induced skin reaction, with a minimally visible residual scar.Keywords: radiotherapy, acute radiodermatitis, growth factors, cytokines
