A distributed fMRI-based signature for the subjective experience of fear

Feng Zhou; Weihua Zhao; Ziyu Qi; Yayuan Geng; Shuxia Yao; Keith M. Kendrick; Tor D. Wager; Benjamin Becker

doi:10.1038/s41467-021-26977-3

Nature Communications (Nov 2021)

A distributed fMRI-based signature for the subjective experience of fear

Feng Zhou,
Weihua Zhao,
Ziyu Qi,
Yayuan Geng,
Shuxia Yao,
Keith M. Kendrick,
Tor D. Wager,
Benjamin Becker

Affiliations

Feng Zhou: Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China
Weihua Zhao: Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China
Ziyu Qi: Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China
Yayuan Geng: Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China
Shuxia Yao: Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China
Keith M. Kendrick: Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China
Tor D. Wager: Department of Psychological and Brain Sciences, Dartmouth College
Benjamin Becker: Clinical Hospital of Chengdu Brain Science Institute, MOE Key Laboratory for Neuroinformation, University of Electronic Science and Technology of China

DOI: https://doi.org/10.1038/s41467-021-26977-3
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 16

Abstract

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The brain systems underlying fear experience are debated. Here the authors develop an fMRI-based neural signature for fear and show that fear is represented in distributed brain systems rather than isolated ‘fear centers’.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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