Clinical Case Reports (Jun 2023)

Complete hematologic response after belinostat treatment and allogeneic stem cell transplantation for multiple relapsed/refractory angioimmunoblastic T‐cell lymphoma: A case report

  • Vincent Camus,
  • Pascaline Etancelin,
  • Fanny Drieux,
  • Elena‐Liana Veresezan,
  • Jean‐Michel Picquenot,
  • Dominique Penther,
  • Mathieu Viennot,
  • Philippe Ruminy,
  • Nathalie Contentin,
  • Emilie Lemasle,
  • Stéphane Leprêtre,
  • Sydney Dubois,
  • Juliette Penichoux,
  • Aspasia Stamatoullas,
  • Alexandra Zduniak,
  • Hélène Lanic,
  • Fabrice Jardin

DOI
https://doi.org/10.1002/ccr3.7623
Journal volume & issue
Vol. 11, no. 6
pp. n/a – n/a

Abstract

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Key Clinical Message This case report highlights the potential of belinostat for the treatment of relapsed/refractory peripheral T‐cell lymphomas, for which effective therapies are still scarce. Abstract Peripheral T‐cell lymphomas have an aggressive disease course associated with poor outcomes. We report a young patient with highly pretreated relapsed/refractory nodal follicular helper T‐cell lymphoma (angioimmunoblastic‐type [nTFHL‐AI]), who successfully received an allogeneic stem cell transplantation following belinostat therapy. The complete hematologic response achieved has lasted more than 2 years.

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