Risk factors for healthcare-associated candidemia in adults hospitalized with SARS-CoV-2 infection

Zachary M. Most; John J. Hanna; Alexander P. Radunsky; Lauren N. Cooper; Christoph U. Lehmann; Trish M. Perl; Richard J. Medford

doi:10.1017/ash.2024.25

Antimicrobial Stewardship & Healthcare Epidemiology (Jan 2024)

Risk factors for healthcare-associated candidemia in adults hospitalized with SARS-CoV-2 infection

Zachary M. Most,
John J. Hanna,
Alexander P. Radunsky,
Lauren N. Cooper,
Christoph U. Lehmann,
Trish M. Perl,
Richard J. Medford

Affiliations

Zachary M. Most: ORCiD; Division of Infectious Disease, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA
John J. Hanna: Division of Infectious Disease and Geographic Medicine, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA Clinical Informatics Center, University of Texas Southwestern Medical Center, Dallas, TX, USA Division of Infectious Diseases, Department of Internal Medicine, Brody School of Medicine, Greenville, NC, USA Information Services, ECU Health, Greenville, NC, USA
Alexander P. Radunsky: ORCiD; Division of Infectious Disease and Geographic Medicine, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA
Lauren N. Cooper: ORCiD; Clinical Informatics Center, University of Texas Southwestern Medical Center, Dallas, TX, USA
Christoph U. Lehmann: Clinical Informatics Center, University of Texas Southwestern Medical Center, Dallas, TX, USA Peter O’Donnell School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX, USA Lyda Hill Department of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, TX, USA
Trish M. Perl: Division of Infectious Disease and Geographic Medicine, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA Peter O’Donnell School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX, USA
Richard J. Medford: ORCiD; Division of Infectious Disease and Geographic Medicine, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA Clinical Informatics Center, University of Texas Southwestern Medical Center, Dallas, TX, USA Division of Infectious Diseases, Department of Internal Medicine, Brody School of Medicine, Greenville, NC, USA Information Services, ECU Health, Greenville, NC, USA

DOI: https://doi.org/10.1017/ash.2024.25
Journal volume & issue: Vol. 4

Abstract

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Analyzing data from a national deidentified electronic health record-based data set using a matched case–control study design, we found that antibiotic use and severity of illness were independent risk factors for healthcare-associated candidemia in adult patients hospitalized with SARS-CoV-2 infection. Interleukin-6 inhibitor and corticosteroid use were not independent risk factors.

Published in Antimicrobial Stewardship & Healthcare Epidemiology

ISSN: 2732-494X (Online)
Publisher: Cambridge University Press
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases; Medicine: Public aspects of medicine
Website: https://www.cambridge.org/core/journals/antimicrobial-stewardship-and-healthcare-epidemiology

About the journal