Journal of Chemistry (Jan 2013)
Preparation of α-Bromoketones Involving the Reaction of Enol Triethyl Borates with N-Bromosuccinimide
Abstract
The ketones (5α- and 5β-cholestan-3-one and (1S,7aS)-1-tert-butoxy-hexahydro-7a-methyl-1H-inden-5-one) were efficiently α-monobrominated by treatment of the corresponding enol triethyl borates with N-bromosuccinimide (NBS).