Asian Journal of Andrology (Jan 2015)
Behavioral mechanisms of mammalian sperm guidance
- Serafín Pérez Cerezales,
- Sergii Boryshpolets,
- Michael Eisenbach
Affiliations
- Serafín Pérez Cerezales
- Sergii Boryshpolets
- Michael Eisenbach
- DOI
- https://doi.org/10.4103/1008-682X.154308
- Journal volume & issue
-
Vol. 17,
no. 4
pp. 628 – 632
Abstract
In mammals, sperm guidance in the oviduct appears essential for successful sperm arrival at the oocyte. Hitherto, three different potential sperm guidance mechanisms have been recognized: thermotaxis, rheotaxis, and chemotaxis, each of them using specific stimuli - a temperature gradient, fluid flow, and a chemoattractant gradient, respectively. Here, we review sperm behavioral in these mechanisms and indicate commonalities and differences between them.
Keywords
- gene regulation
- Musashi
- Musashi-1
- Musashi-2
- posttranscriptional control
- RNA binding proteins
- spermatogenesis
- splicing
- testis
- translation
- cell fate
- cell stress
- importin
- karyopherin
- nucleocytoplasmic transport
- spermatid
- spermatocyte
- spermatogenesis
- artificial insemination
- biomarker
- fertility
- fertilization
- flow cytometry
- infertility
- nanotechnology
- oocyte activation
- Postacrosomal Sheath WWI Domain Binding Protein
- sperm
- SPTRX3
- thioredoxin
- ubiquitin
- ATP binding cassette transporters
- albumin
- high-density lipoprotein
- lipid rafts
- membrane fluidity
- membrane microdomains
- membrane packing
- oxysterols
- reverse cholesterol transport
- sterol transporters
- egg
- fertilization
- heat shock protein A2
- molecular chaperone
- sperm
- sperm-egg interactions
- dehydrogenases
- oxidases
- peroxiredoxins
- reactive oxygen species
- spermatozoa
- thiols
- thioredoxins
- antigen-presenting cells
- autoimmunity
- dendritic cells
- epididymis
- macrophages
- peripheral tolerance
- sperm maturation
- spermatozoa
- genomics
- male infertility
- proteomics
- sperm chromatin
- sperm epigenetics
- sperm DNA damage
- paternal genome
- offspring
- infertility
- chemotaxis
- rheotaxis
- sperm behavior
- sperm motility
- thermotaxis
