Arabian Journal of Chemistry (Sep 2016)
Synthesis, antimicrobial and antioxidant activities of 2-oxo-6-phenyl-2-yl-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-1,2-dihydro pyridin-3-carbonitriles and their derivatives
Abstract
2-Oxo-4-(2′-phenyl-5′-substituted 1H-indol-3′-yl)-6-phenylpyridin-3-carbnitriles (2a–c) and its derivatives containing 1,2,4-triazole (4a–c), thiazolo[3,2-b][1,2,4]triazole (5a–c), hydrazide (6a–c), pyrazolones (7a–c) and (8a–c) were synthesized. Structures of all these previously unknown compounds were confirmed by their spectral studies and elemental analysis. The compounds were screened for their antioxidant and antimicrobial activities.
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