Thoracic Cancer (Apr 2023)
Chinese expert consensus on the diagnosis and treatment of thymic epithelial tumors
- Chunwei Xu,
- Yongchang Zhang,
- Wenxian Wang,
- Qian Wang,
- Ziming Li,
- Zhengbo Song,
- Jiandong Wang,
- Jinpu Yu,
- Jingjing Liu,
- Shirong Zhang,
- Xiuyu Cai,
- Ming Wu,
- Ping Zhan,
- Hongbing Liu,
- Tangfeng Lv,
- Liyun Miao,
- Lingfeng Min,
- Jiancheng Li,
- Baogang Liu,
- Jingping Yuan,
- Zhansheng Jiang,
- Gen Lin,
- Xiaohui Chen,
- Xingxiang Pu,
- Chuangzhou Rao,
- Dongqing Lv,
- Zongyang Yu,
- Xiaoyan Li,
- Chuanhao Tang,
- Chengzhi Zhou,
- Junping Zhang,
- Hui Guo,
- Qian Chu,
- Rui Meng,
- Xuewen Liu,
- Jingxun Wu,
- Xiao Hu,
- Min Fang,
- Jin Zhou,
- Zhengfei Zhu,
- Xiaofeng Chen,
- Weiwei Pan,
- Fei Pang,
- Yuxiang Zhou,
- Qijie Jian,
- Kai Wang,
- Liping Wang,
- Youcai Zhu,
- Guocai Yang,
- Xinqing Lin,
- Jing Cai,
- Lijun Liang,
- Huijing Feng,
- Lin Wang,
- Yingying Du,
- Wang Yao,
- Xuefei Shi,
- Xiaomin Niu,
- Dongmei Yuan,
- Yanwen Yao,
- Jianhui Huang,
- Yinbin Zhang,
- Pingli Sun,
- Hong Wang,
- Mingxiang Ye,
- Dong Wang,
- Zhaofeng Wang,
- Yue Hao,
- Zhen Wang,
- Bing Wan,
- Donglai Lv,
- Genhua Yu,
- Anna Li,
- Jin Kang,
- Jiatao Zhang,
- Chao Zhang,
- Huafei Chen,
- Lin Shi,
- Leiguang Ye,
- Gaoming Wang,
- Yina Wang,
- Feng Gao,
- Wei Zhou,
- Chunxiu Hu,
- Jianguo Wei,
- Bihui Li,
- Zhongwu Li,
- Yuan Li,
- Zhefeng Liu,
- Nong Yang,
- Lin Wu,
- Qiming Wang,
- Wenbin Huang,
- Zhuan Hong,
- Guansong Wang,
- Meiyu Fang,
- Yong Fang,
- Xixu Zhu,
- Kaiqi Du,
- Jiansong Ji,
- Yi Shen,
- Yiping Zhang,
- Shenglin Ma,
- Yong Song,
- Yuanzhi Lu,
- Anwen Liu,
- Wenfeng Fang,
- Wenzhao Zhong
Affiliations
- Chunwei Xu
- Institute of Cancer and Basic Medicine (ICBM) Chinese Academy of Sciences Hangzhou People's Republic of China
- Yongchang Zhang
- Department of Medical Oncology Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University Changsha People's Republic of China
- Wenxian Wang
- Department of Chemotherapy Chinese Academy of Sciences University Cancer Hospital (Zhejiang Cancer Hospital) Zhejiang People's Republic of China
- Qian Wang
- Department of Respiratory Medicine Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine Nanjing People's Republic of China
- Ziming Li
- Department of Shanghai Lung Cancer Center, Shanghai Chest Hospital Shanghai Jiao Tong University Shanghai People's Republic of China
- Zhengbo Song
- Department of Chemotherapy Chinese Academy of Sciences University Cancer Hospital (Zhejiang Cancer Hospital) Zhejiang People's Republic of China
- Jiandong Wang
- Department of Pathology, Affiliated Jinling Hospital Medical School of Nanjing University Nanjing People's Republic of China
- Jinpu Yu
- Department of Cancer Molecular Diagnostics Core Tianjin Medical University Cancer Institute and Hospital Tianjin People's Republic of China
- Jingjing Liu
- Department of Thoracic Cancer Jilin Cancer Hospital Jilin People's Republic of China
- Shirong Zhang
- Translational Medicine Research Center, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People's Hospital, Cancer Center Zhejiang University School of Medicine Hangzhou People's Republic of China
- Xiuyu Cai
- Department of VIP Inpatient, Sun Yet‐Sen University Cancer Center, State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine Guangzhou People's Republic of China
- Ming Wu
- Department of Thoracic Surgery, Second Affiliated Hospital of Zhejiang University School of Medicine, Cancer Center Zhejiang University Hangzhou People's Republic of China
- Ping Zhan
- Department of Respiratory Medicine, Affiliated Jinling Hospital Medical School of Nanjing University Nanjing People's Republic of China
- Hongbing Liu
- Department of Respiratory Medicine, Affiliated Jinling Hospital Medical School of Nanjing University Nanjing People's Republic of China
- Tangfeng Lv
- Department of Respiratory Medicine, Affiliated Jinling Hospital Medical School of Nanjing University Nanjing People's Republic of China
- Liyun Miao
- Department of Respiratory Medicine, Affiliated Drum Tower Hospital Medical School of Nanjing University Nanjing People's Republic of China
- Lingfeng Min
- Department of Respiratory Medicine Clinical Medical School of Yangzhou University, Subei People's Hospital of Jiangsu Province Yangzhou People's Republic of China
- Jiancheng Li
- Department of Radiation Oncology Fujian Medical University Cancer Hospital & Fujian Cancer Hospital Fuzhou People's Republic of China
- Baogang Liu
- Department of Oncology Harbin Medical University Cancer Hospital Harbin People's Republic of China
- Jingping Yuan
- Department of Pathology Renmin Hospital of Wuhan University Wuhan People's Republic of China
- Zhansheng Jiang
- Derpartment of Integrative Oncology Tianjin Medical University Cancer Institute and Hospital Tianjin People's Republic of China
- Gen Lin
- Department of Medical Oncology Fujian Medical University Cancer Hospital & Fujian Cancer Hospital Fuzhou People's Republic of China
- Xiaohui Chen
- Department of Thoracic Surgery Fujian Medical University Cancer Hospital & Fujian Cancer Hospital Fuzhou People's Republic of China
- Xingxiang Pu
- Department of Medical Oncology, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University Changsha People's Republic of China
- Chuangzhou Rao
- Department of Radiotherapy and Chemotherapy, Hwamei Hospital University of Chinese Academy of Sciences Ningbo People's Republic of China
- Dongqing Lv
- Department of Pulmonary Medicine Taizhou Hospital of Wenzhou Medical University Taizhou People's Republic of China
- Zongyang Yu
- Department of Respiratory Medicine, the 900th Hospital of the Joint Logistics Team (the Former Fuzhou General Hospital) Fujian Medical University Fuzhou People's Republic of China
- Xiaoyan Li
- Department of Oncology Beijing Tiantan Hospital, Capital Medical University Beijing People's Republic of China
- Chuanhao Tang
- Department of Medical Oncology Peking University International Hospital Beijing People's Republic of China
- Chengzhi Zhou
- State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University(The First Affiliated Hospital of Guangzhou Medical University) Guangzhou People's Republic of China
- Junping Zhang
- Department of Thoracic Oncology Shanxi Academy of Medical Sciences, Shanxi Bethune Hospital Taiyuan People's Republic of China
- Hui Guo
- Department of Medical Oncology The First Affiliated Hospital of Xi'an Jiaotong University Xi'an People's Republic of China
- Qian Chu
- Department of Oncology, Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology Wuhan People's Republic of China
- Rui Meng
- Cancer Center, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan People's Republic of China
- Xuewen Liu
- Department of Oncology, the Third Xiangya Hospital Central South University Changsha People's Republic of China
- Jingxun Wu
- Department of Medical Oncology, the First Affiliated Hospital of Medicine Xiamen University Xiamen People's Republic of China
- Xiao Hu
- Zhejiang Key Laboratory of Radiation Oncology Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital) Zhejiang People's Republic of China
- Min Fang
- Zhejiang Key Laboratory of Radiation Oncology Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital) Zhejiang People's Republic of China
- Jin Zhou
- Department of Medical Oncology, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine University of Electronic Science and Technology Chengdu People's Republic of China
- Zhengfei Zhu
- Department of Radiation Oncology Fudan University Shanghai Cancer Center Shanghai People's Republic of China
- Xiaofeng Chen
- Department of Oncology Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital Nanjing People's Republic of China
- Weiwei Pan
- Department of Cell Biology, College of Medicine Jiaxing University Jiaxing People's Republic of China
- Fei Pang
- Department of Medical Shanghai OrigiMed Co, Ltd Shanghai People's Republic of China
- Yuxiang Zhou
- Department of Medical Shanghai OrigiMed Co, Ltd Shanghai People's Republic of China
- Qijie Jian
- Department of Medical Shanghai OrigiMed Co, Ltd Shanghai People's Republic of China
- Kai Wang
- Department of Medical Shanghai OrigiMed Co, Ltd Shanghai People's Republic of China
- Liping Wang
- Department of Oncology Baotou Cancer Hospital Baotou People's Republic of China
- Youcai Zhu
- Department of Thoracic Disease Diagnosis and Treatment Center, Zhejiang Rongjun Hospital The Third Affiliated Hospital of Jiaxing University Jiaxing People's Republic of China
- Guocai Yang
- Department of Thoracic Surgery Zhoushan Hospital, Wenzhou Medical University Zhejiang People's Republic of China
- Xinqing Lin
- State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University(The First Affiliated Hospital of Guangzhou Medical University) Guangzhou People's Republic of China
- Jing Cai
- Department of Oncology Second Affiliated Hospital of Nanchang University Nanchang People's Republic of China
- Lijun Liang
- Department of Thoracic Surgery, Second Affiliated Hospital of Zhejiang University School of Medicine, Cancer Center Zhejiang University Hangzhou People's Republic of China
- Huijing Feng
- Department of Thoracic Oncology Shanxi Academy of Medical Sciences, Shanxi Bethune Hospital Taiyuan People's Republic of China
- Lin Wang
- Department of Pathology, Shanxi Academy of Medical Sciences Shanxi Bethune Hospital Taiyuan People's Republic of China
- Yingying Du
- Department of Oncology The First Affiliated Hospital of Anhui Medical University Hefei People's Republic of China
- Wang Yao
- Department of Interventional Oncology, The First Affiliated Hospital Sun Yat‐sen University Guangzhou People's Republic of China
- Xuefei Shi
- Department of Respiratory Medicine, Huzhou Hospital Zhejiang University School of Medicine Huzhou People's Republic of China
- Xiaomin Niu
- Department of Shanghai Lung Cancer Center, Shanghai Chest Hospital Shanghai Jiao Tong University Shanghai People's Republic of China
- Dongmei Yuan
- Department of Respiratory Medicine, Affiliated Jinling Hospital Medical School of Nanjing University Nanjing People's Republic of China
- Yanwen Yao
- Department of Respiratory Medicine, Affiliated Jinling Hospital Medical School of Nanjing University Nanjing People's Republic of China
- Jianhui Huang
- Department of Oncology Lishui Municipal Central Hospital Lishui People's Republic of China
- Yinbin Zhang
- Department of Oncology the Second Affiliated Hospital of Medical College, Xi'an Jiaotong University Xi'an People's Republic of China
- Pingli Sun
- Department of Pathology The Second Hospital of Jilin University Changchun People's Republic of China
- Hong Wang
- Senior Department of Oncology The 5th Medical Center of PLA General Hospital Beijing People's Republic of China
- Mingxiang Ye
- Department of Respiratory Medicine, Affiliated Jinling Hospital Medical School of Nanjing University Nanjing People's Republic of China
- Dong Wang
- Department of Respiratory Medicine, Affiliated Jinling Hospital Medical School of Nanjing University Nanjing People's Republic of China
- Zhaofeng Wang
- Department of Respiratory Medicine, Affiliated Jinling Hospital Medical School of Nanjing University Nanjing People's Republic of China
- Yue Hao
- Department of Chemotherapy Chinese Academy of Sciences University Cancer Hospital (Zhejiang Cancer Hospital) Zhejiang People's Republic of China
- Zhen Wang
- Department of Radiation Oncology, Affiliated Jinling Hospital Medical School of Nanjing University Nanjing People's Republic of China
- Bing Wan
- Department of Respiratory Medicine The Affiliated Jiangning Hospital of Nanjing Medical University Nanjing People's Republic of China
- Donglai Lv
- Department of Clinical Oncology The 901 Hospital of Joint Logistics Support Force of People Liberation Army Hefei People's Republic of China
- Genhua Yu
- Department of Radiation Oncology Zhebei Mingzhou Hospital Huzhou People's Republic of China
- Anna Li
- Guangdong Lung Cancer Institute Guangdong Provincial Laboratory of Translational Medicine in Lung Cancer, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine Guangzhou People's Republic of China
- Jin Kang
- Guangdong Lung Cancer Institute Guangdong Provincial Laboratory of Translational Medicine in Lung Cancer, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine Guangzhou People's Republic of China
- Jiatao Zhang
- Guangdong Lung Cancer Institute Guangdong Provincial Laboratory of Translational Medicine in Lung Cancer, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine Guangzhou People's Republic of China
- Chao Zhang
- Guangdong Lung Cancer Institute Guangdong Provincial Laboratory of Translational Medicine in Lung Cancer, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine Guangzhou People's Republic of China
- Huafei Chen
- Department of Thoracic Disease Diagnosis and Treatment Center, Zhejiang Rongjun Hospital The Third Affiliated Hospital of Jiaxing University Jiaxing People's Republic of China
- Lin Shi
- Department of Respiratory Medicine Zhongshan Hospital, Fudan University Shanghai People's Republic of China
- Leiguang Ye
- Department of Oncology Harbin Medical University Cancer Hospital Harbin People's Republic of China
- Gaoming Wang
- Department of Thoracic Surgery Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical University Xuzhou People's Republic of China
- Yina Wang
- Department of Oncology The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou People's Republic of China
- Feng Gao
- Department of Thoracic Surgery The Fourth Hospital of Hebei Medical University Shijiazhuang People's Republic of China
- Wei Zhou
- Institute of Cancer and Basic Medicine (ICBM) Chinese Academy of Sciences Hangzhou People's Republic of China
- Chunxiu Hu
- Department of Cancer Radiotherapy and Chemotherapy Zhejiang Queue Hospital Quzhou People's Republic of China
- Jianguo Wei
- Department of Pahtology Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine) Shaoxing People's Republic of China
- Bihui Li
- Department of Oncology The Second Affiliated Hospital of Guilin Medical University Guilin People's Republic of China
- Zhongwu Li
- Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Pathology Peking University Cancer Hospital & Institute Beijing People's Republic of China
- Yuan Li
- Department of Pathology Fudan University Shanghai Cancer Center Shanghai People's Republic of China
- Zhefeng Liu
- Senior Department of Oncology The 5th Medical Center of PLA General Hospital Beijing People's Republic of China
- Nong Yang
- Department of Respiratory Medicine, Affiliated Jinling Hospital Medical School of Nanjing University Nanjing People's Republic of China
- Lin Wu
- Department of Medical Oncology, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine Central South University Changsha People's Republic of China
- Qiming Wang
- Department of Internal Medicine The Affiliated Cancer Hospital of Zhengzhou University Henan Cancer Hospital Zhengzhou People's Republic of China
- Wenbin Huang
- Department of Pathology the First Affiliated Hospital of Henan University of Science and Technology Luoyang People's Republic of China
- Zhuan Hong
- Department of Medical Oncology, Jiangsu Cancer Hospital Nanjing Medical University Affiliated Cancer Hospital Nanjing People's Republic of China
- Guansong Wang
- Institute of Respiratory Diseases Xinqiao Hospital, Third Military Medical University Chongqing People's Republic of China
- Meiyu Fang
- Department of Medical Oncology Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University Changsha People's Republic of China
- Yong Fang
- Department of Medical Oncology Sir Run Run Shaw Hospital, Zhejiang University Hangzhou People's Republic of China
- Xixu Zhu
- Department of Radiation Oncology, Affiliated Jinling Hospital Medical School of Nanjing University Nanjing People's Republic of China
- Kaiqi Du
- Department of Thoracic Disease Diagnosis and Treatment Center, Zhejiang Rongjun Hospital The Third Affiliated Hospital of Jiaxing University Jiaxing People's Republic of China
- Jiansong Ji
- Department of Radiology Lishui Municipal Central Hospital Lishui People's Republic of China
- Yi Shen
- Department of Thoracic Surgery, Affiliated Jinling Hospital Medical School of Nanjing University Nanjing People's Republic of China
- Yiping Zhang
- Department of Medical Oncology Lung Cancer and Gastrointestinal Unit, Hunan Cancer Hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University Changsha People's Republic of China
- Shenglin Ma
- Department of Oncology Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou Cancer Hospital, Cancer Center, Zhejiang University School of Medicine Hangzhou People's Republic of China
- Yong Song
- Department of Respiratory Medicine, Affiliated Jinling Hospital Medical School of Nanjing University Nanjing People's Republic of China
- Yuanzhi Lu
- Department of Clinical Pathology The First Affiliated Hospital Of Jinan University Guangzhou People's Republic of China
- Anwen Liu
- Department of Oncology Second Affiliated Hospital of Nanchang University Nanchang People's Republic of China
- Wenfeng Fang
- Department of Medical Oncology Sun Yat‐sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Guangzhou People's Republic of China
- Wenzhao Zhong
- Guangdong Lung Cancer Institute Guangdong Provincial Laboratory of Translational Medicine in Lung Cancer, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, School of Medicine Guangzhou People's Republic of China
- DOI
- https://doi.org/10.1111/1759-7714.14847
- Journal volume & issue
-
Vol. 14,
no. 12
pp. 1102 – 1117
Abstract
Abstract Thymic epithelial tumors (TETs) are a relatively rare type of thoracic tumor, accounting for less than 1% of all tumors. The incidence of TETs is about 3.93/10000 in China, slightly higher than that of European and American countries. For resectable TETs, complete surgical resection is recommended. Radiotherapy or chemotherapy may be used as postoperative adjuvant treatment. Treatment for advanced, unresectable TETs consist mainly of radiotherapy and chemotherapy, but there is a lack of standard first‐ and second‐line treatment regimens. Recently, targeted therapies and immune checkpoint inhibitors have shown promising outcomes in TETs. Based on the currently available clinical evidences and the opinions of the national experts, the Thymic Oncology Group of Yangtze River Delta Lung Cancer Cooperation Group (East China LUng caNcer Group, ECLUNG; Youth Committee) established this Chinese expert consensus on the clinical diagnosis and treatment of TETs, covering the epidemiology, diagnosis, treatment, prognosis and follow‐up of TETs.
Keywords