Randomized phase II trial of avelumab alone or in combination with cetuximab for patients with previously treated, locally advanced, or metastatic squamous cell anal carcinoma: the CARACAS study

• Matteo Fassan,
• Fotios Loupakis,
• Sara Lonardi,
• Federica Morano,
• Mariaelena Casagrande,
• Filippo Pietrantonio,
• Gianluca Masi,
• Marco Messina,
• Andrea Sartore-Bianchi,
• Paola Del Bianco,
• Francesca Bergamo,
• Angela Buonadonna,
• Vittorina Zagonel,
• Massimiliano Spada,
• Monica Ronzoni,
• Salvatore Corallo,
• Michele Prisciandaro,
• Giovanni Luca Frassineti,
• Alessandra Anna Prete,
• Vincenzo Formica,
• Domenico Cristiano Corsi,
• Corrado Orciuolo,
• Maria Giulia Zampino,
• Mario Scartozzi,
• Stefania Mosconi,
• Margherita Ratti,
• Emiliano Tamburini,
• Valentina Vettore

Affiliations

Matteo Fassan

Department of Medicine (DIMED), Pathology Unit, University of Padua, Padua, Veneto, Italy, University of Padova, Padova, Veneto, Italy

Fotios Loupakis

Istituto Oncologico Veneto Istituto di Ricovero e Cura a Carattere Scientifico, Department of Oncology 1, veneto Institute of Oncology IOV—IRCCS, Padua, Italy

Sara Lonardi

Istituto Oncologico Veneto Istituto di Ricovero e Cura a Carattere Scientifico, Department of Oncology 1, veneto Institute of Oncology IOV—IRCCS, Padua, Italy

Federica Morano

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy

Mariaelena Casagrande

Department of Oncology, Azienda Sanitaria Universitaria Integrata di Udine, Udine, Italy

Filippo Pietrantonio

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy

Gianluca Masi

Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy

Marco Messina

Department of Oncology, Fondazione Istituto G. Giglio, Cefalù, Italy

Andrea Sartore-Bianchi

Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy

Paola Del Bianco

Clinical Research Unit, Veneto Institute of Oncology IOV—IRCCS, Padua, Italy

Francesca Bergamo

Istituto Oncologico Veneto Istituto di Ricovero e Cura a Carattere Scientifico, Department of Oncology 1, veneto Institute of Oncology IOV—IRCCS, Padua, Italy

Angela Buonadonna

Unit of Medical Oncology and Cancer Prevention, Centro di Riferimento Oncologico di Aviano IRCCS, Aviano, Italy

Vittorina Zagonel

Istituto Oncologico Veneto Istituto di Ricovero e Cura a Carattere Scientifico, Department of Oncology 1, veneto Institute of Oncology IOV—IRCCS, Padua, Italy

Massimiliano Spada

Department of Oncology, Fondazione Istituto G. Giglio, Cefalù, Italy

Monica Ronzoni

Oncologia Medica, IRCCS Ospedale San Raffaele, Milan, Italy

Salvatore Corallo

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy

Michele Prisciandaro

Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy

Giovanni Luca Frassineti

Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori Dino Amadori (IRST), Meldola, Italy

Alessandra Anna Prete

Istituto Oncologico Veneto Istituto di Ricovero e Cura a Carattere Scientifico, Department of Oncology 1, veneto Institute of Oncology IOV—IRCCS, Padua, Italy

Vincenzo Formica

Medical Oncology Unit, Policlinico Tor Vergata, Rome, Italy

Domenico Cristiano Corsi

Medical Oncology Unit, Ospedale San Giovanni Calibita Fatebenefratelli, Rome, Italy

Corrado Orciuolo

Oncology Unit, Department of Radiology, Oncology and Human Pathology, Sapienza University of Roma, Rome, Italy

Maria Giulia Zampino

Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology—IRCCS, Milan, Italy

Mario Scartozzi

Department of Medical Oncology, University of Cagliari, Cagliari, Italy

Stefania Mosconi

Department of Medical Oncology, Ospedale Papa Giovanni XXIII, Bergamo, Italy

Margherita Ratti

Division of Oncology, Hospital Trust of Cremona, Cremona, Italy

Emiliano Tamburini

Department of Oncology and Palliative Care, Cardinale G Panico, Tricase City Hospital, Tricase, Italy

Valentina Vettore

Istituto Oncologico Veneto Istituto di Ricovero e Cura a Carattere Scientifico, Department of Oncology 1, veneto Institute of Oncology IOV—IRCCS, Padua, Italy