3-Chloro-r-2,c-6-bis(4-fluorophenyl)-3-methylpiperidin-4-one

Abstract

The title compound, C18H16ClF2NO, contains one independent molecule in the asymmetric unit, with the piperidin-4-one ring adopting a slightly distorted chair conformation and an equatorial orientation of all the substituents except chlorine. A single weak intermolecular C—H...O interaction influences the crystal packing, forming infinite one-dimensional zigzag chains along the a axis. The structure was refined as a two-component inversion twin.

Keywords

• crystal structure
• substituted piperidones
• piperidin-4-one