Prostaglandin E2 receptor Ptger4b regulates female-specific peptidergic neurons and female sexual receptivity in medaka

Thomas Fleming; Yukiko Kikuchi; Mikoto Nakajo; Masaya Tachizawa; Tomoaki Inazumi; Soken Tsuchiya; Yukihiko Sugimoto; Daisuke Saito; Mikita Suyama; Yasuyuki Ohkawa; Takashi Baba; Ken-ichirou Morohashi; Kataaki Okubo

doi:10.1038/s42003-022-04195-x

Communications Biology (Nov 2022)

Prostaglandin E2 receptor Ptger4b regulates female-specific peptidergic neurons and female sexual receptivity in medaka

Thomas Fleming,
Yukiko Kikuchi,
Mikoto Nakajo,
Masaya Tachizawa,
Tomoaki Inazumi,
Soken Tsuchiya,
Yukihiko Sugimoto,
Daisuke Saito,
Mikita Suyama,
Yasuyuki Ohkawa,
Takashi Baba,
Ken-ichirou Morohashi,
Kataaki Okubo

Affiliations

Thomas Fleming: Department of Aquatic Bioscience, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Yukiko Kikuchi: Department of Aquatic Bioscience, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Mikoto Nakajo: Department of Aquatic Bioscience, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Masaya Tachizawa: Department of Aquatic Bioscience, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Tomoaki Inazumi: Department of Pharmaceutical Biochemistry, Graduate School of Pharmaceutical Sciences, Kumamoto University
Soken Tsuchiya: Department of Pharmaceutical Biochemistry, Graduate School of Pharmaceutical Sciences, Kumamoto University
Yukihiko Sugimoto: Department of Pharmaceutical Biochemistry, Graduate School of Pharmaceutical Sciences, Kumamoto University
Daisuke Saito: Division of Bioinformatics, Medical Institute of Bioregulation, Kyushu University
Mikita Suyama: Division of Bioinformatics, Medical Institute of Bioregulation, Kyushu University
Yasuyuki Ohkawa: Division of Transcriptomics, Medical Institute of Bioregulation, Kyushu University
Takashi Baba: Department of Molecular Biology, Graduate School of Medical Sciences, Kyushu University
Ken-ichirou Morohashi: Department of Molecular Biology, Graduate School of Medical Sciences, Kyushu University
Kataaki Okubo: Department of Aquatic Bioscience, Graduate School of Agricultural and Life Sciences, The University of Tokyo

DOI: https://doi.org/10.1038/s42003-022-04195-x
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 13

Abstract

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Prostaglandin E2 signaling mediates the estrogenic regulation of peptidergic neuronal activity and female receptivity via the ptger4b gene pathway in Japanese rice fish.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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