Drugs in Context (May 2024)

Rapid response on facial psoriasis to bimekizumab: case series

  • Nicoletta Bernardini,
  • Annunziata Dattola,
  • Giacomo Caldarola,
  • Diego Orsini,
  • Chiara Assorgi,
  • Alessandra D’Amore,
  • Giulia Maretti,
  • Antonio Giovanni Richetta,
  • Ersilia Tolino,
  • Nevena Skroza,
  • Concetta Potenza

DOI
https://doi.org/10.7573/dic.2024-1-4
Journal volume & issue
Vol. 13
pp. 1 – 6

Abstract

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Psoriasis is a chronic inflammatory disease that can affect any part of the body but, when it appears in certain areas, like the face, it can have a very significant psychological impact. Biologics, in particular IL-17 and IL-23 drug inhibitors, have shown relevant clinical efficacy in the management of psoriatic lesions in difficult-to-treat areas. In post hoc analysis of phase III trials in plaque psoriasis, bimekizumab has shown safety and complete clearance of high-impact areas. However, these studies did not focus on the effect of bimekizumab on facial lesions. Therefore, this case series represents the first clinical real-life experience of rapid and successful management of facial psoriasis with bimekizumab in six patients.

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