Wheat Breeding, Transcription Factories, and Genetic Interactions: New Perspectives

Abstract

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Epistatic interactions and negative heterosis have been shown to be associated with interchromosomal interactions in wheat. Physical gene-gene interactions between co-regulated genes clustered in “transcription factories” have been documented, and a genome-wide atlas of functionally paired, interacting regulatory elements and genes of wheat recently produced. Integration of these new studies on gene and regulatory element interactions, co-regulation of gene expression in “transcription factories,” and epigenetics generates new perspectives for wheat breeding and trait enhancement.

Keywords

• wheat
• transcription factories
• epigenetics
• heterosis
• breeding