Frontiers in Oncology (Dec 2022)

Safety profile of robotic-assisted transperineal MRI-US-fusion guided biopsy of the prostate

  • Manuel Walter,
  • Pawel Trotsenko,
  • Hanns-Christian Breit,
  • Nicola Keller,
  • Anja Meyer,
  • David Jean Winkel,
  • Hans Helge Seifert,
  • Christian Wetterauer,
  • Christian Wetterauer,
  • Christian Wetterauer

DOI
https://doi.org/10.3389/fonc.2022.1025355
Journal volume & issue
Vol. 12

Abstract

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IntroductionRobotic-assisted transperineal MRI-US-fusion guided biopsy of the prostate is a novel and highly accurate procedure. The aim of this study was to evaluate the MonaLisa prostate biopsy system in terms of safety, tolerability, and patient-related outcomes.MethodsThis prospective study included 228 patients, who had undergone Robotic-assisted transperineal MRI-US-fusion guided biopsy of the prostate at the University Hospital Basel between January 2020 and June 2022. Peri-operative side effects, functional outcomes and patient satisfaction were assessed.ResultsMean pain score on the day of biopsy was 1.3 points on VAS, which remained constant on the day after biopsy. Overall, 32 of 228 patients (14%) developed grade I complications according to Clavien-Dindo classification. No higher-grade complications occurred. Gross haematuria, hematospermia and acute urinary retention occurred in 145/228 (63.6%), 98/228 (43%) and 32/228 (14%) patients, respectively. One patient (0.4%) developed urinary tract infection.ConclusionsRobotic-assisted transperineal MRI-US-fusion guided biopsy of the prostate performed under general anesthesia is a safe and well tolerated procedure. This technique allows to omit perioperative prophylaxis and at the same time minimizes the risk of infectious complications. We attribute the favorable risk profile and tolerability to the minimal invasive approach via two entry points.

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