Biosensors (Aug 2022)

A Detection-Service-Mobile Three-Terminal Software Platform for Point-of-Care Infectious Disease Detection System

  • Xiangyi Su,
  • Yile Fang,
  • Haoran Liu,
  • Yue Wang,
  • Minjie Ji,
  • Zhu Chen,
  • Hui Chen,
  • Song Li,
  • Yan Deng,
  • Lian Jin,
  • Yuanying Zhang,
  • Murugan Ramalingam,
  • Nongyue He

DOI
https://doi.org/10.3390/bios12090684
Journal volume & issue
Vol. 12, no. 9
p. 684

Abstract

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The traditional infectious disease detection process is cumbersome, and there is only a single application scenario. In recent years, with the development of the medical industry and the impact of the epidemic situation, the number of infectious disease detection instruments based on nursing point detection has been increasing. Due to this trend, many detection instruments and massive detection data urgently need to be managed. In addition, the experiment failed due to the abnormal fluorescence curve generated by a human operator or sample impurities. Finally, the geographic information system has also played an active role in spreading and preventing infectious diseases; this paper designs a “detection-service-mobile” three-terminal system to realize the control of diagnostic instruments and the comprehensive management of data. Machine learning is used to classify the enlarged curve and calculate the cycle threshold of the positive curve; combined with a geographic information system, the detection results are marked on the mobile terminal map to realize the visual display of the positive results of nucleic acid amplification detection and the early warning of infectious diseases. In the research, applying this system to portable field pathogen detection is feasible and practical.

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