PLoS ONE (Jan 2014)

The relation of rapid changes in obesity measures to lipid profile - insights from a nationwide metabolic health survey in 444 Polish cities.

  • Bernhard M Kaess,
  • Jacek Jóźwiak,
  • Christopher P Nelson,
  • Witold Lukas,
  • Mirosław Mastej,
  • Adam Windak,
  • Tomasz Tomasik,
  • Władysław Grzeszczak,
  • Andrzej Tykarski,
  • Jerzy Gąsowski,
  • Izabella Ślęzak-Prochazka,
  • Andrzej Ślęzak,
  • Fadi J Charchar,
  • Naveed Sattar,
  • John R Thompson,
  • Nilesh J Samani,
  • Maciej Tomaszewski

DOI
https://doi.org/10.1371/journal.pone.0086837
Journal volume & issue
Vol. 9, no. 1
p. e86837

Abstract

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ObjectiveThe impact of fast changes in obesity indices on other measures of metabolic health is poorly defined in the general population. Using the Polish accession to the European Union as a model of political and social transformation we examined how an expected rapid increase in body mass index (BMI) and waist circumference relates to changes in lipid profile, both at the population and personal level.MethodsThrough primary care centres in 444 Polish cities, two cross-sectional nationwide population-based surveys (LIPIDOGRAM 2004 and LIPIDOGRAM 2006) examined 15,404 and 15,453 adult individuals in 2004 and 2006, respectively. A separate prospective sample of 1,840 individuals recruited in 2004 had a follow-up in 2006 (LIPIDOGRAM PLUS).ResultsTwo years after Polish accession to European Union, mean population BMI and waist circumference increased by 0.6% and 0.9%, respectively. This tracked with a 7.6% drop in HDL-cholesterol and a 2.1% increase in triglycerides (all pConclusionsModerate changes in obesity measures tracked with a significant deterioration in measures of pro-atherogenic dyslipidaemia at both personal and population level. These associations were predominantly driven by factors not measureable directly through either BMI or waist circumference.