Проблемы особо опасных инфекций (Aug 2008)

Production of S-layer proteins by Different <i>Bacillus anthracis</i> Strains

  • I. A. Barkova,
  • V. V. Alexeev,
  • A. V. Lipnitsky,
  • A. M. Barkov,
  • L. V. Bukhantsova

DOI
https://doi.org/10.21055/0370-1069-2008-4(98)-29-32
Journal volume & issue
Vol. 0, no. 4(98)
pp. 29 – 32

Abstract

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Investigated were antigenic properties of proteins produced by B. anthracis strains STI (рХО1+, рХО2-), Davies (рХО1-, рХО2+), 81/1TR (рХО1-, рХО2-), eluated in void volume (fraction 1) at division of cultural filtrates (CF) on superfine sefacryle S-300. Sera to fractions 1 of B. anthracis STI, 81/1TR and Davies CF were shown to contain antibodies to different antigens. The proteins identified with the help of sera were referred to antigens of В. anthracis S-layer relaying on м.м. 94 kDa, characteristic for S-layer proteins, localization on superficial cell structure, and independence of their production from virulence plasmids.

Keywords