Journal of Clinical and Diagnostic Research (Sep 2019)
Hyperuricaemia, Hypoparathyroidism and Acute Hypercalcaemia: Unusual Complications in Extrapulmonary Tuberculosis
Abstract
Hypercalcaemia may occur in patients with pulmonary tuberculosis because of abnormal extrarenal production of 1,25-dihydroxy Vitamin D3 by activated macrophages in granulomatous tissues. In Extrapulmonary Tuberculosis, derangements of calcium, Parathyroid levels are usually not seen. Rarely, serum calcium levels are raised with a normal vitamin D levels in background of an adequate sunlight exposure. Here, authors report a case of a patient with tubercular meningitis who presented with hypercalcaemia, hyperuricaemia, and hypoparathyroidism.
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