Specific residues in the cytoplasmic domain modulate photocurrent kinetics of channelrhodopsin from Klebsormidium nitens

Rintaro Tashiro; Kumari Sushmita; Shoko Hososhima; Sunita Sharma; Suneel Kateriya; Hideki Kandori; Satoshi P. Tsunoda

doi:10.1038/s42003-021-01755-5

Communications Biology (Feb 2021)

Specific residues in the cytoplasmic domain modulate photocurrent kinetics of channelrhodopsin from Klebsormidium nitens

Rintaro Tashiro,
Kumari Sushmita,
Shoko Hososhima,
Sunita Sharma,
Suneel Kateriya,
Hideki Kandori,
Satoshi P. Tsunoda

Affiliations

Rintaro Tashiro: Department of Life Science and Applied Chemistry, Nagoya Institute of Technology
Kumari Sushmita: Laboratory of Optobiology, School of Biotechnology, Jawaharlal Nehru University
Shoko Hososhima: Department of Life Science and Applied Chemistry, Nagoya Institute of Technology
Sunita Sharma: Laboratory of Optobiology, School of Biotechnology, Jawaharlal Nehru University
Suneel Kateriya: Laboratory of Optobiology, School of Biotechnology, Jawaharlal Nehru University
Hideki Kandori: Department of Life Science and Applied Chemistry, Nagoya Institute of Technology
Satoshi P. Tsunoda: Department of Life Science and Applied Chemistry, Nagoya Institute of Technology

DOI: https://doi.org/10.1038/s42003-021-01755-5
Journal volume & issue: Vol. 4, no. 1
pp. 1 – 10

Abstract

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Tashiro et al. describe a new channelrhodopsin variant from a terrestrial algal species and the role of the C-terminal domain in regulatory function. This far-blue-shifted channelrhodopsin may contribute to optogenetic tool research in the future.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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