An Interesting Case of Acute Section Encephalitic Syndrome with Pancytopenia and Splenomegaly

Abstract

Human Parvovirus infection is a rare condition causing encephalitis as well as pancytopenia. Similarly patient of Wilson disease presenting as hepatic encephalopathy as an initial manifestation is also a rare phenomenon. A previously healthy 20-year-old female patient presented as acute encephalitis syndrome with hepatitis and pancytopenia. Bone marrow examination showed the presence of inclusion bodies and PCR (Polymerase Chain Reaction) showed the presence of DNA of human parvo virus B19. Patient was suspected as a case of Wilson’s disease due to the persistence of splenomegaly and radiological findings and was confirmed by increased 24 hours urinary copper and low level of serum ceruloplasmin. Patient was treated symptomatically and gained consciousness and pancytopenia improved over course of time.

Keywords

• human parvovirus b 19
• serum ceruloplasmin
• wilson’s disease