Application of aptamers in regenerative medicine

Zhaohui Luo; Zhaohui Luo; Shimin Chen; Shimin Chen; Jing Zhou; Chong Wang; Kai Li; Jia Liu; Yujin Tang; Liqiang Wang

doi:10.3389/fbioe.2022.976960

Frontiers in Bioengineering and Biotechnology (Aug 2022)

Application of aptamers in regenerative medicine

Zhaohui Luo,
Zhaohui Luo,
Shimin Chen,
Shimin Chen,
Jing Zhou,
Chong Wang,
Kai Li,
Jia Liu,
Yujin Tang,
Liqiang Wang

Affiliations

Zhaohui Luo: Youjiang Medical University for Nationalities, Baise, Guangxi, China
Zhaohui Luo: Guangxi Key Laboratory of basic and translational research of Bone and Joint Degenerative Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases, Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China
Shimin Chen: Guangxi Botanical Garden of Medicinal Plants, Nanning, China
Shimin Chen: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China
Jing Zhou: Youjiang Medical University for Nationalities, Baise, Guangxi, China
Chong Wang: School of Mechanical Engineering, Dongguan University of Technology, Dongguan, Guangdong, China
Kai Li: Academy of Orthopedics, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases, The Third Affiliated Hospital of Southern Medical University, Guangzhou, China
Jia Liu: Guangxi Key Laboratory of basic and translational research of Bone and Joint Degenerative Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases, Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China
Yujin Tang: Guangxi Key Laboratory of basic and translational research of Bone and Joint Degenerative Diseases, Guangxi Biomedical Materials Engineering Research Center for Bone and Joint Degenerative Diseases, Department of Orthopedics, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, China
Liqiang Wang: State Key Laboratory of Metal Matrix Composites, School of Material Science and Engineering, Shanghai Jiao Tong University, Shanghai, China

DOI: https://doi.org/10.3389/fbioe.2022.976960
Journal volume & issue: Vol. 10

Abstract

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Regenerative medicine is a discipline that studies how to use biological and engineering principles and operation methods to repair and regenerate damaged tissues and organs. Until now, regenerative medicine has focused mainly on the in-depth study of the pathological mechanism of diseases, the further development and application of new drugs, and tissue engineering technology strategies. The emergence of aptamers has supplemented the development methods and types of new drugs and enriched the application elements of tissue engineering technology, injecting new vitality into regenerative medicine. The role and application status of aptamers screened in recent years in various tissue regeneration and repair are reviewed, and the prospects and challenges of aptamer technology are discussed, providing a basis for the design and application of aptamers in long-term transformation.

Published in Frontiers in Bioengineering and Biotechnology

ISSN: 2296-4185 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Technology: Chemical technology: Biotechnology
Website: http://www.frontiersin.org/bioengineering_and_biotechnology

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