Nature Communications (Aug 2020)

The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development

  • Dong Won Kim,
  • Parris Whitney Washington,
  • Zoe Qianyi Wang,
  • Sonia Hao Lin,
  • Changyu Sun,
  • Basma Taleb Ismail,
  • Hong Wang,
  • Lizhi Jiang,
  • Seth Blackshaw

DOI
https://doi.org/10.1038/s41467-020-18231-z
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 11

Abstract

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The cellular and molecular mechanisms regulating hypothalamic patterning and differentiation are unclear. Here, the authors profiled the transcriptome of the developing hypothalamus at single cell level, providing a resource to hypothalamic development in health and disease.