In Vitro Antimicrobial Evaluation, Single-Point Resistance Study, and Radiosterilization of Novel Pyrazole Incorporating Thiazol-4-one/Thiophene Derivatives as Dual DNA Gyrase and DHFR Inhibitors against MDR Pathogens

• Hazem Ali Mohamed,
• Yousry A. Ammar,
• Gameel A.M. Elhagali,
• Hassan A. Eyada,
• Dina S. Aboul-Magd,
• Ahmed Ragab

Affiliations

Hazem Ali Mohamed

Chemistry Department, Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt

Yousry A. Ammar

Chemistry Department, Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt

Gameel A.M. Elhagali

Chemistry Department, Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt

Hassan A. Eyada

Chemistry Department, Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt

Dina S. Aboul-Magd

Drug Radiation​ Research Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority, Cairo, Egypt

Ahmed Ragab

Chemistry Department, Faculty of Science (Boys), Al-Azhar University, Cairo, Egypt