The study (a) assesses the life cycle energy consumption and air emissions impacts of battery electric buses (e-buses) and conventional buses operated in Vietnam, and (b) compares them with those of hydrogen buses. The results indicate that e-buses and hydrogen buses are preferred options compared to conventional buses in terms of energy consumption, GHG emissions and other air quality impacts over their whole life cycle. Life cycle energy consumption of diesel buses is triple that of e-buses, and is significantly higher than that of hydrogen buses. Replacing conventional buses with e-buses can reduce energy consumption by 50%. For GHG emissions and air quality impacts, the adoption of electric and hydrogen mobility in replacement of conventional buses will reduce GHG emissions by 39%, and other impacts related to air quality by 13% to 90%.