Cancer Reports (Jun 2024)

A case report of renal cell carcinoma metastasis revealed through late‐onset thyroid nodules

  • Abolfazl Khalafi‐Nezhad,
  • Ali Zamani,
  • Mahya Amini,
  • Shahrzad Negahban

DOI
https://doi.org/10.1002/cnr2.2113
Journal volume & issue
Vol. 7, no. 6
pp. n/a – n/a

Abstract

Read online

Abstract Background Renal cell carcinoma (RCC) is one of the most common and prevalent cancers all around the world with a prevalence of 3%. Approximately twenty percent of patients present with metastasis at the time of diagnosis, while late metastasis in renal cell carcinoma is a quite familiar phenomenon. Head and neck and particularly thyroid metastasis from RCC are rare events. Case We present a case of a 75‐year‐old woman who developed thyroid nodules 13 years after nephrectomy for RCC. Diagnosis confirmed metastatic RCC through clinical history, histomorphology, and immunohistochemistry. Imaging studies revealed thyroid lesions without metastasis in other organs. The patient underwent total thyroidectomy and remains symptom‐free after 2 years of follow‐up. Conclusion This case highlights the importance of considering metastatic lesions is crucial in managing thyroid nodules in patients with a history of cancer, particularly RCC.

Keywords