Open Medicine (Jan 2016)

Integrated therapeutic approach to giant solitary fibrous tumor of the pleura: report of a case and review of the literature

  • Perrotta Fabio,
  • Cerqua Francesco Saverio,
  • Cammarata Antonino,
  • Izzo Alessandro,
  • Bergaminelli Carlo,
  • Curcio Carlo,
  • Guarino Carmine,
  • Grella Edoardo,
  • Forzano Imma,
  • Cennamo Antonio,
  • Tafuri Domenico,
  • Rocca Aldo,
  • Bianco Andrea,
  • Mazzarella Gennaro

DOI
https://doi.org/10.1515/med-2016-0042
Journal volume & issue
Vol. 11, no. 1
pp. 220 – 225

Abstract

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The fibrous tumors of the pleura are rare primary tumors, accounting for 5% of malignant pleural neoplasms, which generally originate from sub-mesothelial mesenchymal tissue of the visceral pleura. These tumours generally exhibit clinical benign behavior although 12% of solitary fibrous tumors can be malignant and have worse outcomes. These tumors are considered “giant” when the lesion > 15 cm. Surgical treatment is the best choice for both benign and malignant neoplasms. We retrospectively analyzed the main case series of giant fibrous tumors of the pleura. In addition we report our experience of a 76-year-old woman treated by pre-surgical embolization involving implantation of vascular plugs. Surgery was successfully carried out without complications; imaging and functional assessment 6 months post intervention demonstrated both the absence of recurrence and improvement of lung function parameters.

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