Beilstein Journal of Organic Chemistry (Aug 2019)

A review of the total syntheses of triptolide

  • Xiang Zhang,
  • Zaozao Xiao,
  • Hongtao Xu

DOI
https://doi.org/10.3762/bjoc.15.194
Journal volume & issue
Vol. 15, no. 1
pp. 1984 – 1995

Abstract

Read online

Triptolide is a complex triepoxide diterpene natural product that has attracted considerable interest in the organic chemistry and medicinal chemistry societies due to its intriguing structural features and multiple promising biological activities. In this review, progress in the total syntheses of triptolide are systematically summarized. We hope to gain a better understanding of the field and provide constructive suggestions for future studies of triptolide.

Keywords