Sensitivity to treatment and score bands of the Infants and Toddlers Dermatology Quality of Life questionnaireCapsule Summary

Pavel V. Chernyshov, MD, PhD; Servando E. Marron, MD; Michael J. Boffa, MD, MSc; Nives Pustišek, MD, PhD; Liana Manolache, MD, PhD; Talia Kakourou, MD, PhD; Monique Cachia, MD; Tetiana Svyatenko, MD, PhD, DrSc; Dimitra Koumaki, MD, PhD; Andrii V. Chernyshov, MD, PhD; Lucia Tomas-Aragones, PhD

JAAD International (Mar 2023)

Sensitivity to treatment and score bands of the Infants and Toddlers Dermatology Quality of Life questionnaireCapsule Summary

Pavel V. Chernyshov, MD, PhD,
Servando E. Marron, MD,
Michael J. Boffa, MD, MSc,
Nives Pustišek, MD, PhD,
Liana Manolache, MD, PhD,
Talia Kakourou, MD, PhD,
Monique Cachia, MD,
Tetiana Svyatenko, MD, PhD, DrSc,
Dimitra Koumaki, MD, PhD,
Andrii V. Chernyshov, MD, PhD,
Lucia Tomas-Aragones, PhD

Affiliations

Pavel V. Chernyshov, MD, PhD: Department of Dermatology and Venereology, National Medical University, Kiev, Ukraine; Correspondence to: Pavel V. Chernyshov, MD, PhD, Department of Dermatology and Venereology, National Medical University, 13 Bulvar Shevchenko, Kiev, 01601, Ukraine.
Servando E. Marron, MD: Department of Dermatology, University Hospital Miguel Servet, Aragon Psychodermatology Research Group (GAI+PD), Zaragoza, Spain
Michael J. Boffa, MD, MSc: Department of Dermatology, Mater Dei Hospital, Msida, Malta
Nives Pustišek, MD, PhD: Children's Hospital Zagreb, Medical School, University of Zagreb, Zagreb, Croatia
Liana Manolache, MD, PhD: Dermatology, Dali Medical, Bucharest, Romania
Talia Kakourou, MD, PhD: First Pediatric Department of Athens University, Aghia Sophia Children’s Hospital, Athens, Greece
Monique Cachia, MD: Department of Dermatology, Mater Dei Hospital, Msida, Malta
Tetiana Svyatenko, MD, PhD, DrSc: Department of Skin and Venereal Diseases, Dnipro State Medical University, Dnipro, Ukraine
Dimitra Koumaki, MD, PhD: Department of Dermatology and Venereology, University Hospital of Heraklion, Heraklion, Crete, Greece
Andrii V. Chernyshov, MD, PhD: Department of Cellular Radiobiology, State Institution “National Research Center for Radiation Medicine of National Academy of Medical Sciences of Ukraine”, Kiev, Ukraine
Lucia Tomas-Aragones, PhD: Department of Psychology, University of Zaragoza, Zaragoza, Spain

Journal volume & issue: Vol. 10
pp. 61 – 67

Abstract

Read online

Background: The Infants and Toddlers Dermatology Quality of Life (InToDermQoL) questionnaire is the first dermatology-specific proxy health related QoL instrument for children from birth to 4 years. Score meaning bands and the sensitivity to successful therapeutic intervention are important to interpret the clinical meaning of an instrument. Objective: The aim of the present study was to check the sensitivity to successful therapeutic intervention and establish score bands of the InToDermQoL questionnaire. Methods: Parents or grandparents of 424 children with skin diseases from Spain, Malta, Croatia, Romania, Greece, and Ukraine filled in national language versions of the InToDermQoL questionnaire. Disease severity of children with atopic dermatitis was assessed by SCORAD (Scoring atopic dermatitis). Cohen’s d was used to assess the responsiveness of the instrument. Results: The mean total InToDermQoL scores significantly decreased after treatment. Severity grading of the SCORAD scores gave stratification of the InToDermQoL severity grades based on 95% confidence intervals. Scores below a calculated minimal important difference of 2 corresponded to no effect on patient’s health related QoL. Limitations: Score banding may be slightly different across patient population and study context. Conclusion: All 3 age-specific versions of the InToDermQoL questionnaire showed sensitivity to treatment. Score bands for the InToDermQoL questionnaire have been established.

Published in JAAD International

ISSN: 2666-3287 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Dermatology
Website: https://www.journals.elsevier.com/jaad-international

About the journal

Abstract

Keywords