Epidemiological and clinical aspects of HIV associated dementia at the University Hospital of Point G

Abstract

Introduction Dementia is a real fact in the course of Human Immunodeficiency Virus infection. In Mali, no specific studies have been done to estimate its frequency. The objective of this study is -to evaluate the frequency of Human Immunodeficiency Virus associated dementia at the university hospital of Point G -to assess the clinical profile and the risk factors of Human Immunodeficiency Virus associated dementia at the university hospital of Point G Methods It is a prospective study design extended from July 2009 to August 2010. 113 Human Immunodeficiency Virus positive patients aged 16 years old and plus have been recruited from the department of neurology, the infectious disease department and the emergency department at the university hospital of Point G. Data was collected using clinical evaluation reporting forms. Patients were interviewed and evaluated using the international HIV dementia scale. The international HIV dementia scale total score is 12. A score less or equal to 10 is considered to be abnormal and may indicate HIV associated dementia. Results Using the International HIV Dementia Scale, we found a significant frequency of dementia; 69.9%. Advanced clinical state, low CD4 count, AIDS stage, low level of education and the decline of the activity of daily life, were the risk factors significantly associated with Human Immunodeficiency Virus dementia. Conclusion The International Human Immunodeficiency Virus Dementia Scale is a screening toll for dementia in HIV-infected patient. 69.9% of the HIH positive patients were demented with a score less or equal to 10. Its adaptation is socio-culturally convenient in Mali