Scientific Reports (Jul 2017)

Changes of corneal tomography in patients with congenital blepharoptosis

  • Tiepei Zhu,
  • Xin Ye,
  • Peifang Xu,
  • Jingyi Wang,
  • Huina Zhang,
  • Hailong Ni,
  • Zhaoan Su,
  • Juan Ye

DOI
https://doi.org/10.1038/s41598-017-06823-7
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 8

Abstract

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Abstract The study aimed to evaluate the effect of drooped eyelid on corneal tomography in congenital blepharoptosis patients. Sixty-four patients with congenital blepharoptosis and 64 age- and sex- matched healthy subjects were included. According to the eyelid margin to corneal light reflex distance (MRD), eyes with congenital blepharoptosis were categorized as mild, moderate, or severe. The eyes were scanned using the rotating Scheimpflug camera. Increased topometric parameters were observed in moderate and severe blepharoptosis. Back corneal elevations at the thinnest point were significant higher for mild (P = 0.009), moderate (P < 0.001), and severe (P < 0.001) congenital blepharoptosis compared with controls. Maximum Ambrósio’s relational thickness (ART) was decreased in eyes with severe blepharoptosis (P < 0.001). Fnal D values were significantly higher in moderate (P < 0.001) and severe blepharoptosis (P < 0.001) groups than that of controls. There were significant correlations between MRD and most corneal tomographic parameters. Our findings indicated there was a trend toward subclinical keratoconus-like changes in the corneas of congenital blepharoptosis, with the increase of ptosis severity.