Opportunities and challenges of three-dimensional printing technology in pharmaceutical formulation development

Mengsuo Cui; Hao Pan; Yupei Su; Dongyang Fang; Sen Qiao; Pingtian Ding; Weisan Pan

Acta Pharmaceutica Sinica B (Aug 2021)

Opportunities and challenges of three-dimensional printing technology in pharmaceutical formulation development

Mengsuo Cui,
Hao Pan,
Yupei Su,
Dongyang Fang,
Sen Qiao,
Pingtian Ding,
Weisan Pan

Affiliations

Mengsuo Cui: Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
Hao Pan: School of Pharmacy, Liaoning University, 66 Chongshan Middle Road, Shenyang 110036, China
Yupei Su: Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
Dongyang Fang: Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
Sen Qiao: Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China
Pingtian Ding: Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China; Corresponding authors. Tel./fax: +86 02443520515 (Pingtian Ding); Tel./fax: +86 02443520533 (Weisan Pan).
Weisan Pan: Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China; Corresponding authors. Tel./fax: +86 02443520515 (Pingtian Ding); Tel./fax: +86 02443520533 (Weisan Pan).

Journal volume & issue: Vol. 11, no. 8
pp. 2488 – 2504

Abstract

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Three-dimensional printing is a technology that prints the products layer-by-layer, in which materials are deposited according to the digital model designed by computer aided design (CAD) software. This technology has competitive advantages regarding product design complexity, product personalization, and on-demand manufacturing. The emergence of 3D technology provides innovative strategies and new ways to develop novel drug delivery systems. This review summarizes the application of 3D printing technologies in the pharmaceutical field, with an emphasis on the advantages of 3D printing technologies for achieving rapid drug delivery, personalized drug delivery, compound drug delivery and customized drug delivery. In addition, this article illustrates the limitations and challenges of 3D printing technologies in the field of pharmaceutical formulation development.

Published in Acta Pharmaceutica Sinica B

ISSN: 2211-3835 (Print); 2211-3843 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Therapeutics. Pharmacology
Website: http://www.journals.elsevier.com/acta-pharmaceutica-sinica-b

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Abstract

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