LIVER TRANSPLANTATION AND HBV INFECTION

Abstract

The paper describes the modern approaches in treatment of hepatitis B virus (HBV)-infected patients who underwent liver transplantation. The patients with HBV liver cirrhosis and waiting for orthotopic liver transplantation (OLT) have to receive long-term therapy with nucleos(t)ide analogs right up to liver transplantation. The paper discuss the different schemes of prophylaxis of recurrent HBV infection during post-transplantation and specific treatment of HBV infection after liver transplantation as well as possibilities of orthotopic liver transplantation for patients with liver cancer.

Keywords

• liver transplantation
• recurrent hbv infection
• de novo hepatitis b
• immunoglobulin against hbv (hbig)
• lamivudine
• entecavir