Recent studies on anti-aging compounds with Saccharomyces cerevisiae as a model organism

Abstract

Extension of lifespan and amelioration of aging-associated phenotypes have been targets of many studies. Some of the established methods of increasing lifespan including dietary restriction and genetic manipulation are difficult to apply to humans, and their side effects are hard to predict. For that reason, it is important to discover compounds that can mimic the anti-aging actions or induce lifespan extension through different metabolisms within the cell. Here we summarize the recent studies to test various types of compounds and materials using budding yeast that show potential anti-aging effects. Keywords: Anti-aging agent, Budding yeast, Lifespan extension, Chronological lifespan, Replicative lifespan