Splenic infarction secondary to polycythemia Vera: Case report and literature review

Qusay Abdoh, PhD; Mohammad Alnees, MD; Islam Rajab, MD; Alaa Zayed, MD; Hamza Salim, MD; Abdelkarim Barqawi, PhD; Riad Amer, PhD

Radiology Case Reports (Oct 2023)

Splenic infarction secondary to polycythemia Vera: Case report and literature review

Qusay Abdoh, PhD,
Mohammad Alnees, MD,
Islam Rajab, MD,
Alaa Zayed, MD,
Hamza Salim, MD,
Abdelkarim Barqawi, PhD,
Riad Amer, PhD

Affiliations

Qusay Abdoh, PhD: Department of Medicine, Faculty of Medicine & Health Sciences, An-Najah National University, Nablus, Palestine; Department of Internal Medicine, GI and Endoscopy unit, An-Najah National University Hospital, Nablus, Palestine; Corresponding authors.
Mohammad Alnees, MD: Department of Medicine, Faculty of Medicine & Health Sciences, An-Najah National University, Nablus, Palestine; Corresponding authors.
Islam Rajab, MD: Department of Medicine, Faculty of Medicine & Health Sciences, An-Najah National University, Nablus, Palestine
Alaa Zayed, MD: Department of Medicine, Faculty of Medicine & Health Sciences, An-Najah National University, Nablus, Palestine
Hamza Salim, MD: Department of Medicine, Faculty of Medicine & Health Sciences, An-Najah National University, Nablus, Palestine
Abdelkarim Barqawi, PhD: Department of Medicine, Faculty of Medicine & Health Sciences, An-Najah National University, Nablus, Palestine
Riad Amer, PhD: Department of Medicine, Faculty of Medicine & Health Sciences, An-Najah National University, Nablus, Palestine

Journal volume & issue: Vol. 18, no. 10
pp. 3636 – 3641

Abstract

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Splenic infarction is a medical condition characterized by compromised blood flow to the spleen, resulting in partial or complete organ infarction. This condition is commonly observed in patients with an increased risk of thrombosis, such as those with Polycythemia Vera (PV).A 40-year-old female patient presented with fatigue, weakness, and an enlarged spleen, further tests revealed elevated levels of hemoglobin, white blood cells, and platelets. A bone marrow biopsy and positive Jack II mutations confirmed the diagnosis of PV. The patient later developed portal hypertension, varices, and splenic infarction.This case report aims to raise awareness about the potential complications of PV and emphasizes the importance of early intervention to prevent serious consequences such as splenic infarction. Additionally, it highlights the role of splenectomy in managing complications associated with PV.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

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