International Journal of Infectious Diseases (Apr 2015)

A case of visceral leishmaniasis and pulmonary tuberculosis in a post-partum woman

  • Claudia Colomba,
  • Lucia Adamoli,
  • Marcello Trizzino,
  • Lucia Siracusa,
  • Silvia Bonura,
  • Manlio Tolomeo,
  • Massimo Cajozzo,
  • Giovanni Maurizio Giammanco

DOI
https://doi.org/10.1016/j.ijid.2014.12.020
Journal volume & issue
Vol. 33, no. C
pp. 5 – 6

Abstract

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Visceral leishmaniasis due to Leishmania infantum is a vector-borne zoonotic disease transmitted by sand fly bites endemic in rural or periurban areas of the Mediterranean basin. Pregnancy is accompanied by changes in immune response, mainly a decrease in cellular immunity and a proportional increase in humoral immunity. These physiological events result in increased risk of infection by pathogens whose immunity is based on a T-helper 1 predominant response. We describe a case of visceral leishmaniasis and pulmonary tuberculosis diagnosed in a post-partum woman four days after delivery. The diagnosis of leishmaniasis should be considered in pregnant women with fever and haematologic abnormalities in endemic regions or if a history of exposure in endemic areas is reported.

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