Nature Communications (Jun 2019)

A pan-cancer analysis of synonymous mutations

  • Yogita Sharma,
  • Milad Miladi,
  • Sandeep Dukare,
  • Karine Boulay,
  • Maiwen Caudron-Herger,
  • Matthias Groß,
  • Rolf Backofen,
  • Sven Diederichs

DOI
https://doi.org/10.1038/s41467-019-10489-2
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 14

Abstract

Read online

Synonymous mutations do not alter amino acid sequence but may exert oncogenic effects in other ways. Here, the authors present a catalogue of synonymous mutations in cancer and characterise their properties.